Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.57 |
| ▸ | FABP4 | P15090 | 9/20 | 0.53 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.52 |
| ▸ | FABP3 | P05413 | 3/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | FABP1 | P07148 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5989472 | 0.87 | PLA2G4B (0.52) | PLA2G4BPTPN11PPARGPPARAPPARD | |
| SCHEMBL7641798 | 0.83 | PLA2G4B (0.56) | PLA2G4BPTPN11PPARGPPARA | |
| SCHEMBL5989351 | 0.82 | PLA2G4B (0.56) | PLA2G4BPTPN11PPARGPPARAHDAC8 | |
| SCHEMBL5988269 | 0.82 | PLA2G4B (0.56) | PLA2G4BPTPN11PPARGPPARAHDAC8 | |
| SCHEMBL5989503 | 0.82 | PLA2G4B (0.56) | PLA2G4BPTPN11PPARGPPARAHDAC8 | |
| SCHEMBL5989405 | 0.82 | PLA2G4B (0.56) | PLA2G4BPTPN11PPARGPPARAHDAC8 | |
| SCHEMBL5989330 | 0.81 | PLA2G4B (0.56) | PLA2G4BPTPN11PPARGPPARA | |
| SCHEMBL5434776 | 0.81 | PLA2G4B (0.81) | PLA2G4BPPARGPPARAPPARD | |
| SCHEMBL29207409 | 0.80 | LTA4H (0.56) | PLA2G4BPTPN11HDAC8 | |
| SCHEMBL5057431 | 0.78 | TSHR (0.58) | PLA2G4BPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451827-B2 | MODULATING BLOOD GLUCOSE CONCENTRATION | WYETH | 2002-09-17 | — | — | US | disclosed |