Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 2/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 13/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL764436 | 0.93 | BDKRB1 (0.41) | BDKRB1 | |
| SCHEMBL10121303 | 0.89 | BDKRB1 (0.36) | BDKRB1SUCNR1SCN9AMAPK14 | |
| SCHEMBL764453 | 0.84 | BDKRB1 (0.41) | BDKRB1 | |
| SCHEMBL10121241 | 0.84 | BDKRB1 (0.41) | BDKRB1 | |
| SCHEMBL765183 | 0.84 | BDKRB1 (0.40) | BDKRB1 | |
| SCHEMBL10121111 | 0.82 | BDKRB1 (0.37) | BDKRB1MAPK14 | |
| SCHEMBL10121216 | 0.81 | BDKRB1 (0.41) | BDKRB1SUCNR1MAPK14 | |
| SCHEMBL765844 | 0.81 | BDKRB1 (0.42) | BDKRB1SUCNR1MAPK14 | |
| SCHEMBL765551 | 0.80 | BDKRB1 (0.35) | BDKRB1MAPK14 | |
| SCHEMBL764476 | 0.80 | BDKRB1 (0.35) | BDKRB1SCN9AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |