Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10121111 | 0.90 | BDKRB1 (0.37) | BDKRB1MAPK14PLA2G7PTGER4PTGER2 | |
| SCHEMBL765551 | 0.89 | BDKRB1 (0.35) | BDKRB1MAPK14PLA2G7PTGER4PTGER2 | |
| SCHEMBL10121349 | 0.83 | L3MBTL1 (0.40) | BDKRB1CARM1PRMT6ARPOLB | |
| SCHEMBL765557 | 0.83 | L3MBTL1 (0.40) | BDKRB1ARPOLBALDH1A1TP53 | |
| SCHEMBL10121393 | 0.81 | L3MBTL1 (0.41) | BDKRB1CYP2C19POLBALDH1A1TP53 | |
| SCHEMBL758301 | 0.81 | EPHX2 (0.41) | POLBALDH1A1TP53L3MBTL1 | |
| SCHEMBL10121216 | 0.81 | BDKRB1 (0.41) | BDKRB1MAPK14PLA2G7PTGER4PTGER2 | |
| SCHEMBL765844 | 0.81 | BDKRB1 (0.42) | BDKRB1MAPK14PTGER4PTGER2CYP3A4 | |
| SCHEMBL764477 | 0.80 | L3MBTL1 (0.41) | BDKRB1ARPOLBALDH1A1TP53 | |
| SCHEMBL10121227 | 0.80 | EPHX2 (0.44) | ALDH1A1TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |