Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765643 | 0.92 | BDKRB1 (0.45) | BDKRB1CNR1F10MAPT | |
| SCHEMBL765818 | 0.89 | BDKRB1 (0.41) | BDKRB1MAPK14PTGER4PTGER2DDR2 | |
| SCHEMBL10121214 | 0.87 | BDKRB1 (0.40) | BDKRB1MAPK14PTGER4PTGER2DDR2 | |
| SCHEMBL10121216 | 0.84 | BDKRB1 (0.41) | BDKRB1MAPK14PTGER4PTGER2SUCNR1 | |
| SCHEMBL10121111 | 0.83 | BDKRB1 (0.37) | BDKRB1MAPK14PTGER4PTGER2CYP3A4 | |
| SCHEMBL13191643 | 0.83 | P2RX7 (0.39) | BDKRB1F10MAPT | |
| SCHEMBL12238926 | 0.82 | BDKRB1 (0.49) | BDKRB1 | |
| SCHEMBL10121524 | 0.82 | BDKRB1 (0.44) | BDKRB1F10 | |
| SCHEMBL765551 | 0.81 | BDKRB1 (0.35) | BDKRB1MAPK14PTGER4PTGER2CYP3A4 | |
| SCHEMBL764476 | 0.81 | BDKRB1 (0.35) | BDKRB1MAPK14PTGER4PTGER2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |