SCHEMBL7644499

CC(C)(C)c1ccc(OP(=O)(Oc2ccc(C(C)(C)C)cc2C(C)(C)C)c2ccc(-c3ccc([PH](O)(c4ccc(-c5ccccc5)cc4)c4ccc(C(C)(C)C)cc4C(C)(C)C)cc3)cc2)c(C(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	APEX1	P27695	1/20	0.33

▸	CYP1A2	P05177	1/20	0.33

▸	CYP2C19	P33261	1/20	0.33

▸	RXRA	P19793	1/20	0.32

▸	RXRB	P28702	1/20	0.32

▸	RARA	P10276	1/20	0.31

▸	RARB	P10826	1/20	0.31

▸	RARG	P13631	1/20	0.31

▸	PTPN5	P54829	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7641817	0.88	—	—
SCHEMBL18493502	0.87	CYP2C19 (0.40)	APEX1CYP1A2CYP2C19RXRARXRB
SCHEMBL7640652	0.82	CYP2C19 (0.37)	APEX1CYP1A2CYP2C19RXRARXRB
SCHEMBL868584	0.82	CA1 (0.36)	APEX1CYP1A2CYP2C19RXRARXRB
SCHEMBL30115188	0.82	CA1 (0.36)	APEX1CYP1A2CYP2C19RXRARXRB
SCHEMBL28611162	0.81	RXRA (0.40)	CYP1A2CYP2C19RXRARXRBPTPN5
SCHEMBL7640004	0.79	APEX1 (0.32)	APEX1RXRARXRB
SCHEMBL29268646	0.79	RXRA (0.38)	APEX1CYP1A2CYP2C19RXRARXRB
SCHEMBL7644494	0.79	CYP1A2 (0.35)	APEX1CYP1A2CYP2C19RXRARXRB
SCHEMBL28845791	0.78	PTPN5 (0.40)	APEX1CYP2C19RXRARXRBRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6465548-B1	6-HYDROXYCHROMAN DERIVATIVE WITH PHOSPHORUS AND PHENOLIC ANTIOXIDANTS; HEAT, LIGHT AND OXIDATION STABILITY DURING MOLDING	YOSHITOMI FINE CHEMICALS, LTD. (JP)	2002-10-15	—	—	US	disclosed