Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011679 | 0.93 | THRB (0.65) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL9011627 | 0.93 | THRB (0.65) | THRBHTTMEN1KMT2AMAPT | |
| Hexane SCHEMBL3260754 | 0.93 | THRB (0.65) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL8773 | 0.93 | THRB (0.65) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL28757150 | 0.90 | HTT (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL23356870 | 0.90 | THRB (0.70) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL21044624 | 0.90 | THRB (0.70) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL21044691 | 0.90 | THRB (0.70) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL23356971 | 0.90 | THRB (0.70) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL21341773 | 0.90 | THRB (0.70) | THRBHTTMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2540710-A1 | New precursors for direct radiosynthesis of protected derivatives of O-([18F]Fluoromethyl) tyrosine | Bayer Schering Pharma Aktiengesellschaft (DE) | 2013-01-02 | — | — | EP | disclosed |
| EP-0741716-B1 | DELTA 12,13 -ISO-TAXOL ANALOGS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | UPJOHN CO (US) | 2002-07-24 | — | — | EP | disclosed |
| US-5821363-A | Antineoplastic use and pharmaceutical compositions containing them | PHARMACIA & UPJOHN COMPANY (US) | 1998-10-13 | — | — | US | disclosed |
| EP-0767786-B1 | 7-ETHER-TAXOL ANALOGS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | UPJOHN CO (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0767786-A1 | 7-ETHER-TAXOL ANALOGS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0741716-A1 | DELTA 12,13 -ISO-TAXOL ANALOGS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |
| WO-1996000724-A1 | 7-ETHER-TAXOL ANALOGS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY (US) | 1996-01-11 | — | — | WO | disclosed |
| WO-1995020582-A1 | Δ12,13-ISO-TAXOL ANALOGS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-03 | — | — | WO | disclosed |