Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 9/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | GRM6 | O15303 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | GRM8 | O00222 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 9/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 6/20 | 0.32 |
| ▸ | GRM5 | P41594 | 5/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7130933 | 1.00 | SLC6A4 (0.39) | SLC6A4GRM4CYP1A2GRM6CYP2C19 | |
| SCHEMBL3708394 | 0.85 | KMT2A (0.33) | KMT2A | |
| SCHEMBL3708393 | 0.85 | KMT2A (0.33) | KMT2A | |
| SCHEMBL29552767 | 0.81 | GRM4 (0.38) | SLC6A4GRM4CYP1A2GRM6CYP2C19 | |
| SCHEMBL29552402 | 0.79 | ATM (0.33) | — | |
| SCHEMBL950832 | 0.73 | GRM4 (0.32) | SLC6A4GRM4CYP1A2GRM6CYP2C19 | |
| SCHEMBL3173540 | 0.73 | SLC6A4 (0.32) | SLC6A4 | |
| SCHEMBL2126599 | 0.73 | SLC6A4 (0.35) | SLC6A4GRM4CYP1A2GRM6CYP2C19 | |
| SCHEMBL1518812 | 0.73 | APLNR (0.34) | SLC6A4 | |
| SCHEMBL14053058 | 0.73 | GRM2 (0.46) | GRM2GRM5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024750-A2 | HUMAN KIDNEY TUMOR OVEREXPRESSED MEMBRANE PROTEIN 1 | AEOMICA, INC. (US) | 2002-03-28 | — | — | WO | disclosed |