Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 5/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10121373 | 0.92 | BDKRB1 (0.58) | BDKRB1MAPK14CNR1PTGDR2LMNA | |
| SCHEMBL765809 | 0.85 | BDKRB1 (0.51) | BDKRB1MAPK14CNR1PTGDR2LMNA | |
| SCHEMBL12239081 | 0.84 | BDKRB1 (0.52) | BDKRB1MAPK14CNR1PTGDR2LMNA | |
| SCHEMBL12262023 | 0.84 | BDKRB1 (0.55) | BDKRB1MAPK14CNR1LMNACYP3A4 | |
| SCHEMBL765612 | 0.83 | BDKRB1 (0.45) | BDKRB1MAPK14CNR1CYP3A4LIPG | |
| SCHEMBL765558 | 0.83 | BDKRB1 (0.50) | BDKRB1MAPK14CNR1PTGDR2LMNA | |
| SCHEMBL765555 | 0.82 | BDKRB1 (0.53) | BDKRB1MAPK14CNR1PTGDR2CYP3A4 | |
| SCHEMBL765647 | 0.82 | BDKRB1 (0.52) | BDKRB1MAPK14CNR1PTGDR2LMNA | |
| SCHEMBL765556 | 0.81 | BDKRB1 (0.51) | BDKRB1MAPK14CNR1PTGDR2CYP3A4 | |
| SCHEMBL765624 | 0.81 | MAPK14 (0.53) | BDKRB1MAPK14LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |