Fluoride

Fluoride

SCHEMBL7645016

CC1=Cc2c(-c3cccc4ccccc34)cccc2C1[Zr](C)(C)(=[SiH2])C1C(C)=Cc2c(-c3cccc4ccccc34)cccc21.F.F

nearest known ligand 0.32

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
ALDH1A1 P00352 3/20 0.32
CYP2A6 P11509 1/20 0.32
DHFR P00374 1/20 0.31
KDM4E B2RXH2 3/20 0.31
HPGD P15428 2/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP2 O95551 1/20 0.31
MAPT P10636 1/20 0.31
ALOX12 P18054 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP3 P42574 1/20 0.31
HTT P42858 1/20 0.31
GALK1 P51570 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7150484 0.99 CA12 (0.33) CA12CA1CA2CA9ALDH1A1
Hydrochloric Acid SCHEMBL271719 0.97 CA12 (0.32) CA12CA1CA2CA9ALDH1A1
SCHEMBL8575914 0.95 CA12 (0.31) CA12CA1CA2CA9ALDH1A1
Hydrochloric Acid SCHEMBL6435343 0.94 CA12 (0.30) CA12CA1CA2CA9
SCHEMBL4000317 0.90 ALDH1A1 (0.33) CA12CA1CA2CA9ALDH1A1
Hydrochloric Acid SCHEMBL3401092 0.88 DRD2 (0.30)
Hydrochloric Acid SCHEMBL273551 0.88
SCHEMBL4006349 0.87 PTGS1 (0.35) CA12CA1CA2CA9ALDH1A1
SCHEMBL6917493 0.87 ALDH1A1 (0.36) ALDH1A1HPGDHSD17B10MAPK1L3MBTL1
SCHEMBL27544315 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020143125-A1 Catalyst component and catalyst system having a high polymerization activity for preparing polymers KAMINSKY WALTER (DE) 2002-10-03 US disclosed
US-6303718-B1 PARTICULARLY A CATALYST SYSTEM CONSISTING OF METALLOCENE FLUORIDES AND ALUMINUM ALKYLS BAYER AKTIENGESELLSCHAFT (DE) 2001-10-16 US disclosed