Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | PARG | Q86W56 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643515 | 0.87 | USP2 (0.47) | DPP4DHODHALDH1A1HDAC3HDAC4 | |
| SCHEMBL7638151 | 0.85 | DPP4 (0.46) | DPP4DHODHALDH1A1TSHRHDAC3 | |
| SCHEMBL8018051 | 0.82 | CYP2D6 (0.42) | DHODHALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7642307 | 0.77 | SMN1; SMN2 (0.54) | DPP4ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL7966894 | 0.77 | SMN1; SMN2 (0.39) | ALDH1A1TSHRMEN1KMT2APDE5A | |
| SCHEMBL7635781 | 0.75 | SMN1; SMN2 (0.47) | DPP4ALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL5712356 | 0.73 | MAPK1 (0.45) | ALDH1A1TSHRPARGMEN1KMT2A | |
| SCHEMBL192788 | 0.72 | TP53 (0.51) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL21925 | 0.72 | USP2 (0.47) | ALDH1A1TSHRPARGMEN1KMT2A | |
| SCHEMBL7980392 | 0.72 | SMN1; SMN2 (0.39) | ALDH1A1TSHRMEN1KMT2APDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413973-B1 | SYNERGISTIC WITH A CYANO-PYROLE AND A PHENYLAMIDE AGAINST PHYTOPATHOGENIC FUNGI ON CROP PLANTS; TREATING SEEDS, PLANTS OR SOIL; WHEAT, RYE, BARLEY, MAIZE, CUCURBITS, LAWNS, COTTON, SOYBEANS, COFFEE, SUGARCANE, FRUITS, CUCUMBERS, BEANS | SYNGENTA CROP PROTECTION, INC. | 2002-07-02 | — | — | US | claimed |