Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7635781 | 0.93 | SMN1; SMN2 (0.47) | SMN1; SMN2NPSR1EGFRKMT2ADPP4 | |
| SCHEMBL7643515 | 0.90 | USP2 (0.47) | SMN1; SMN2NPSR1USP2KMT2AMAPK1 | |
| SCHEMBL7638151 | 0.83 | DPP4 (0.46) | DPP4LMNATSHRRXFP1ALDH1A1 | |
| SCHEMBL5712364 | 0.82 | ALDH1A1 (0.59) | SMN1; SMN2USP2KMT2AMAPK1MEN1 | |
| SCHEMBL7887669 | 0.81 | USP2 (0.48) | SMN1; SMN2NPSR1USP2KMT2AMAPK1 | |
| SCHEMBL8700665 | 0.79 | ALDH1A1 (0.52) | SMN1; SMN2USP2MAPK1ALDH1A1 | |
| SCHEMBL192788 | 0.78 | TP53 (0.51) | SMN1; SMN2USP2MAPK1LMNAALDH1A1 | |
| SCHEMBL21925 | 0.78 | USP2 (0.47) | SMN1; SMN2USP2KMT2AMAPK1MEN1 | |
| SCHEMBL7645164 | 0.77 | DPP4 (0.43) | SMN1; SMN2KMT2AMEN1DPP4LMNA | |
| SCHEMBL8423120 | 0.77 | USP2 (0.46) | SMN1; SMN2NPSR1USP2MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413973-B1 | SYNERGISTIC WITH A CYANO-PYROLE AND A PHENYLAMIDE AGAINST PHYTOPATHOGENIC FUNGI ON CROP PLANTS; TREATING SEEDS, PLANTS OR SOIL; WHEAT, RYE, BARLEY, MAIZE, CUCURBITS, LAWNS, COTTON, SOYBEANS, COFFEE, SUGARCANE, FRUITS, CUCUMBERS, BEANS | SYNGENTA CROP PROTECTION, INC. | 2002-07-02 | — | — | US | claimed |