Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RORA | P35398 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | RORB | Q92753 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7642307 | 0.93 | SMN1; SMN2 (0.54) | SMN1; SMN2NPSR1EGFRALDH1A1LMNA | |
| SCHEMBL7638151 | 0.91 | DPP4 (0.46) | ALDH1A1LMNANPY1RNPY2RL3MBTL1 | |
| SCHEMBL7643515 | 0.83 | USP2 (0.47) | SMN1; SMN2NPSR1ALDH1A1LMNANPY1R | |
| SCHEMBL7979203 | 0.76 | MAPK1 (0.40) | SMN1; SMN2NPSR1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7645164 | 0.75 | DPP4 (0.43) | SMN1; SMN2ALDH1A1LMNAL3MBTL1DPP4 | |
| SCHEMBL5712364 | 0.75 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1LMNANPY1RNPY2R | |
| SCHEMBL7887669 | 0.74 | USP2 (0.48) | SMN1; SMN2NPSR1ALDH1A1LMNANPY1R | |
| SCHEMBL8018051 | 0.74 | CYP2D6 (0.42) | ALDH1A1LMNANPY1RNPY2RL3MBTL1 | |
| SCHEMBL10744270 | 0.74 | NPSR1 (0.53) | SMN1; SMN2NPSR1EGFRALDH1A1LMNA | |
| SCHEMBL10741313 | 0.73 | NPSR1 (0.55) | SMN1; SMN2NPSR1EGFRALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413973-B1 | SYNERGISTIC WITH A CYANO-PYROLE AND A PHENYLAMIDE AGAINST PHYTOPATHOGENIC FUNGI ON CROP PLANTS; TREATING SEEDS, PLANTS OR SOIL; WHEAT, RYE, BARLEY, MAIZE, CUCURBITS, LAWNS, COTTON, SOYBEANS, COFFEE, SUGARCANE, FRUITS, CUCUMBERS, BEANS | SYNGENTA CROP PROTECTION, INC. | 2002-07-02 | — | — | US | disclosed |