SCHEMBL7645201

SCHEMBL7645201

O=S(=O)(C(F)(F)C(F)(F)c1ccccc1)C(F)(F)C(F)(F)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA5A P35218 1/20 0.50
CA9 Q16790 1/20 0.50
TSHR P16473 2/20 0.46
ALDH1A1 P00352 1/20 0.46
PTPN1 P18031 3/20 0.41
HSD11B1 P28845 2/20 0.35
KCNN4 O15554 1/20 0.35
HTR6 P50406 1/20 0.35
PSIP1 O75475 1/20 0.34
KIF11 P52732 1/20 0.34
PGK1 P00558 1/20 0.34
PGK2 P07205 1/20 0.34
CYP2C19 P33261 1/20 0.34
NR3C2 P08235 2/20 0.33
FAAH O00519 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
ELANE P08246 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3873862 0.82 PTPN1 (0.49) CA1CA2CA5ACA9TSHR
SCHEMBL9723026 0.76 ALDH1A1 (0.65) CA1CA2CA5ACA9TSHR
SCHEMBL4124865 0.75 CA1 (0.67) CA1CA2CA5ACA9TSHR
SCHEMBL4126418 0.71 CA1 (0.50) CA1CA2CA5ACA9TSHR
SCHEMBL3957533 0.71 CA1 (0.50) CA1CA2CA5ACA9TSHR
SCHEMBL7645200 0.71 CA1 (0.50) CA1CA2CA5ACA9TSHR
SCHEMBL4133244 0.71 CA1 (0.50) CA1CA2CA5ACA9TSHR
SCHEMBL146900 0.71 TSHR (0.58) CA1CA2CA5ACA9TSHR
SCHEMBL21082645 0.71 TSHR (0.58) CA1CA2CA5ACA9TSHR
SCHEMBL17288747 0.71 TSHR (0.58) CA1CA2CA5ACA9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6468445-B2 EXTRACTION USING MIXTURE OF ORGANOBORON COMPOUND, POLYOXYETHYLENE GLYCOL AND ORGANOPHOSPHORUS COMPOUND THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY 2002-10-22 US disclosed
US-20010033814-A1 Novel solvent for the simultaneous recovery of radionuclides from liquid radioactive wastes ROMANOVSKIY VALERIY NICHOLIAVI (RU) 2001-10-25 US disclosed
US-6258333-B1 EXTRACTING REAGENT COMPRISING COMPLEX ORGANOBORON COMPOUNDS, SUBSTITUTED POLYETHYLENE GLYCOLS, AND NEUTRAL ORGANOPHOSPHORUS COMPOUNDS IN DILUENT TO RECOVER CESIUM, STRONTIUM, RARE EARTHS AND ACTINIDES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY 2001-07-10 US disclosed