Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetamidomethylboronic Acid SCHEMBL16190260 | 0.88 | — | — | |
| SCHEMBL7645199 | 0.74 | KDM4E (0.30) | KDM4EMAPK1HIF1A | |
| SCHEMBL29952759 | 0.71 | PREP (0.38) | KDM4E | |
| SCHEMBL10311743 | 0.65 | — | — | |
| SCHEMBL73996 | 0.62 | — | — | |
| SCHEMBL9700989 | 0.62 | — | — | |
| SCHEMBL885113 | 0.62 | KDM4E (0.50) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| Acetic Acid SCHEMBL29127390 | 0.61 | FFAR3 (0.58) | HIF1ATSHRALDH1A1 | |
| Boric Acid SCHEMBL17962526 | 0.61 | THRB (0.43) | TSHRALDH1A1 | |
| Boric Acid SCHEMBL4976220 | 0.61 | THRB (0.43) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022137-A1 | β-LACTAM ANALOGS AND USES THEREFOR | SHOICHET BRIAN K (US) | 2002-03-21 | — | — | WO | disclosed |