Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645749 | 0.81 | ALDH1A1 (0.34) | — | |
| Acetamidomethylboronic Acid SCHEMBL7645202 | 0.74 | KDM4E (0.36) | KDM4EMAPK1HIF1A | |
| SCHEMBL7648550 | 0.73 | NPC1 (0.44) | — | |
| SCHEMBL16178649 | 0.73 | — | — | |
| SCHEMBL7650740 | 0.71 | HPGD (0.51) | KDM4E | |
| SCHEMBL16178407 | 0.69 | — | — | |
| SCHEMBL16178511 | 0.69 | GRIA1 (0.35) | — | |
| SCHEMBL7644181 | 0.69 | HPGD (0.51) | KDM4E | |
| SCHEMBL10624549 | 0.67 | — | — | |
| SCHEMBL18074209 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022137-A1 | β-LACTAM ANALOGS AND USES THEREFOR | SHOICHET BRIAN K (US) | 2002-03-21 | — | — | WO | disclosed |