Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7644715 | 0.79 | GAA (0.35) | GAAHPGDMAPTRECQLALDH1A1 | |
| SCHEMBL6733211 | 0.70 | LMNA (0.38) | GAAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL13722871 | 0.62 | NOTUM (0.62) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6272177 | 0.62 | KMT2A (0.64) | GAAHPGDMAPTALDH1A1MEN1 | |
| SCHEMBL9652604 | 0.61 | GAA (0.39) | GAAHPGDMAPTRECQLALDH1A1 | |
| SCHEMBL4925870 | 0.60 | ADRB1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL14691021 | 0.60 | NOTUM (0.71) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6727748 | 0.59 | MAPT (0.43) | GAAMAPTALDH1A1MEN1KMT2A | |
| Acetic Acid Methyl Ester SCHEMBL837627 | 0.58 | MEN1 (0.50) | GAAHPGDMAPTALDH1A1MEN1 | |
| SCHEMBL10360359 | 0.58 | GAA (0.47) | GAAHPGDMAPTRECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469003-B1 | COMPOUNDS HAVING CELL ADHESION INHIBITING ACTIVITY | NIHON NOHYAKU CO., LTD. (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1130015-A1 | PYRIDAZINONE DERIVATIVES | Nihon Nohyaku Co., Ltd. (JP) | 2001-09-05 | — | — | EP | disclosed |