Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.57 |
| ▸ | DRD3 | P35462 | 4/20 | 0.57 |
| ▸ | PDE3B | Q13370 | 12/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 12/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015641 | 0.83 | PDE3B (0.46) | PDE3BPDE3AHTR1AHTR1DHTR1B | |
| SCHEMBL4314654 | 0.73 | MEN1 (0.58) | DRD2DRD3PDE3BPDE3ALTA4H | |
| SCHEMBL17384760 | 0.73 | LTA4H (0.84) | DRD2DRD3LTA4H | |
| SCHEMBL9825397 | 0.69 | DRD2 (0.62) | DRD2DRD3HTR1A | |
| SCHEMBL20765703 | 0.69 | DRD3 (0.71) | DRD2DRD3 | |
| SCHEMBL1374099 | 0.69 | HRH3 (0.56) | DRD2DRD3PDE3BPDE3A | |
| SCHEMBL1374669 | 0.69 | HDAC1 (0.67) | DRD3PDE3BPDE3A | |
| SCHEMBL11067813 | 0.68 | PDE3B (0.68) | PDE3BPDE3A | |
| SCHEMBL13607015 | 0.68 | HDAC1 (0.54) | DRD3PDE3BPDE3A | |
| SCHEMBL3794904 | 0.68 | MEN1 (0.62) | DRD2DRD3LTA4HHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |