Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | EPOR | P19235 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643175 | 0.73 | UTS2R (0.41) | HDAC1HDAC8UTS2RCYP1A2CYSLTR2 | |
| SCHEMBL28936618 | 0.69 | HDAC1 (0.49) | PPARGPPARAHDAC1HDAC8AKR1C3 | |
| SCHEMBL11701561 | 0.69 | PPARG (0.57) | PPARGPPARAHDAC1UTS2RAKR1C3 | |
| SCHEMBL7645575 | 0.68 | CYP1A2 (0.55) | HDAC1HDAC8CYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL6503796 | 0.67 | HDAC1 (0.65) | HDAC1HDAC8CYP1A2 | |
| SCHEMBL7677415 | 0.66 | HDAC1 (0.49) | HDAC1HDAC8CYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL7450034 | 0.66 | HDAC1 (0.49) | HDAC1HDAC8UTS2RCYP1A2 | |
| SCHEMBL5053268 | 0.66 | FOLH1 (0.47) | PPARGPPARA | |
| SCHEMBL7618200 | 0.65 | CPA3 (0.47) | PPARGPPARAHDAC1HDAC8CYP1A2 | |
| SCHEMBL5054448 | 0.65 | PPARG (0.50) | PPARGPPARAHDAC1HDAC8UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372726-B1 | ADMINISTERING CARBOXYALKYL PHOSPHONATE, PHOSPHORAMIDATE, OR PHOSPHINE OXIDE DERIVATIVE AS ANTITUMOR AGENT TO TREAT CANCER OF PROSTATE GLAND | GUILFORD PHARMACEUTICALS INC. | 2002-04-16 | — | — | US | disclosed |