Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MC5R | P33032 | 1/20 | 0.39 |
| ▸ | MC1R | Q01726 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CPA3 | P15088 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645014 | 0.79 | CHRNB2 (0.37) | CPA3 | |
| SCHEMBL3380508 | 0.74 | CPA3 (0.46) | CYP1A2HDAC1HDAC8CYP3A4CYP2D6 | |
| SCHEMBL7645583 | 0.73 | PPARG (0.42) | UTS2RCYP1A2HDAC1HDAC8CYSLTR2 | |
| SCHEMBL7643171 | 0.72 | CYP1A2 (0.44) | UTS2RCYP1A2HDAC1MC4RMC5R | |
| SCHEMBL6503796 | 0.70 | HDAC1 (0.65) | CYP1A2HDAC1HDAC8CYP3A4CYP2D6 | |
| SCHEMBL28936618 | 0.69 | HDAC1 (0.49) | CYP1A2HDAC1HDAC8CYP3A4CYP2D6 | |
| SCHEMBL7450034 | 0.69 | HDAC1 (0.49) | UTS2RCYP1A2HDAC1HDAC8MC4R | |
| SCHEMBL7677415 | 0.69 | HDAC1 (0.49) | CYP1A2HDAC1HDAC8CYSLTR2CYSLTR1 | |
| SCHEMBL7645575 | 0.69 | CYP1A2 (0.55) | CYP1A2HDAC1HDAC8MC4RMC5R | |
| SCHEMBL4155106 | 0.68 | CPA3 (0.47) | CYP1A2HDAC1HDAC8CYP2D6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151503-A1 | Methods of cancer treatment using naaladase inhibitors | SLUSHER BARBARA S (US) | 2002-10-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151503-A1 | Methods of cancer treatment using naaladase inhibitors | NAALAD2, DNPEP, ACP3 | UTS2R 1436/4885CYP1A2 4583/4885HDAC1 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.