Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.37 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2599340 | 0.85 | S100A4 (1.00) | S100A4MEN1KMT2APOLBLMNA | |
| SCHEMBL31237472 | 0.85 | S100A4 (1.00) | S100A4MEN1KMT2APOLBLMNA | |
| SCHEMBL11549835 | 0.77 | S100A4 (0.54) | S100A4MEN1KMT2APOLBLMNA | |
| SCHEMBL29407826 | 0.73 | S100A4 (0.43) | S100A4MEN1KMT2ALMNAMAPT | |
| SCHEMBL15449470 | 0.72 | MEN1 (0.46) | S100A4MEN1KMT2APOLBLMNA | |
| SCHEMBL19130059 | 0.70 | S100A4 (0.70) | S100A4MEN1KMT2APOLBLMNA | |
| SCHEMBL29006544 | 0.70 | S100A4 (0.50) | S100A4MEN1KMT2APOLBLMNA | |
| SCHEMBL19147624 | 0.70 | S100A4 (0.70) | S100A4MEN1KMT2APOLBLMNA | |
| SCHEMBL10431968 | 0.70 | S100A4 (0.39) | S100A4IDO1DNMT1DNMT3LDNMT3A | |
| SCHEMBL11595145 | 0.69 | S100A4 (0.70) | S100A4MEN1KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6433228-B1 | REACTING AN ANILINE COMPOUND WITH AROMATIC DIAZONIUM COMPOUND, THEN ACRYLIC COMPOUND; CYCLIZATION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-13 | — | — | US | disclosed |