Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PNLIP | P16233 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812335 | 0.91 | KCNMA1 (0.75) | KCNMA1KMT2AMEN1TDP1LMNA | |
| SCHEMBL6819253 | 0.87 | KCNMA1 (0.58) | KCNMA1KMT2AMEN1TDP1LMNA | |
| SCHEMBL6811714 | 0.86 | KMT2A (0.71) | KMT2AMEN1TDP1LMNAALDH1A1 | |
| SCHEMBL6816687 | 0.85 | KCNMA1 (0.56) | KCNMA1KMT2AMEN1TDP1LMNA | |
| SCHEMBL6819355 | 0.84 | MAPK1 (0.66) | KMT2AMEN1TDP1LMNAALDH1A1 | |
| SCHEMBL6816880 | 0.83 | MEN1 (0.64) | KMT2AMEN1TDP1LMNAALDH1A1 | |
| SCHEMBL6816582 | 0.83 | MEN1 (0.65) | KMT2AMEN1TDP1LMNAALOX15 | |
| SCHEMBL6815798 | 0.82 | KCNMA1 (0.53) | KCNMA1KMT2AMEN1TDP1LMNA | |
| SCHEMBL6815397 | 0.82 | FADS1 (0.66) | KMT2AMEN1TDP1LMNAALOX15 | |
| SCHEMBL7645761 | 0.81 | KCNMA1 (0.55) | KCNMA1KMT2AMEN1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462055-B2 | VIRICIDES | WYETH | 2002-10-08 | — | — | US | disclosed |