Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647689 | 0.85 | PTGS2 (0.36) | SMN1; SMN2NPC1RAB9ARECQLKMT2A | |
| SCHEMBL7645867 | 0.73 | CA12 (0.34) | — | |
| SCHEMBL7649613 | 0.71 | L3MBTL1 (0.39) | KMT2AL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL9965803 | 0.71 | KMT2A (0.46) | SMN1; SMN2NPC1RAB9ARECQLKMT2A | |
| SCHEMBL20123195 | 0.71 | KMT2A (0.49) | SMN1; SMN2NPC1RAB9ARECQLKMT2A | |
| SCHEMBL6397317 | 0.70 | SMN1; SMN2 (0.70) | SMN1; SMN2NPC1RAB9ARECQLGAA | |
| SCHEMBL7646054 | 0.68 | SRC (0.46) | KMT2ATDP1CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL31131464 | 0.68 | KMT2A (0.49) | SMN1; SMN2RECQLKMT2ATSHRHPGD | |
| SCHEMBL7909243 | 0.68 | KMT2A (0.49) | SMN1; SMN2RECQLKMT2ATSHRHPGD | |
| SCHEMBL16047247 | 0.68 | KMT2A (0.52) | SMN1; SMN2RECQLKMT2ATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002008235-A1 | MEDICAMENT FOR ORAL APPLICATION, CONTAINING AMINOPROPYL PHOSPHONIC ACID ESTERS AS AN ACTIVE INGREDIENT | JOMAA PHARMAKA GMBH (DE) | 2002-01-31 | — | — | WO | disclosed |