Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 18/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 17/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647704 | 0.89 | ITGA4 (0.47) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7424964 | 0.89 | ITGA4 (0.55) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7647030 | 0.88 | ITGA4 (0.45) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7393718 | 0.87 | ITGA4 (0.54) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7645880 | 0.85 | ITGA4 (0.49) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7536434 | 0.83 | ITGA4 (0.52) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7421221 | 0.83 | ITGA4 (0.55) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7386600 | 0.83 | ITGB1 (0.51) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7648766 | 0.83 | ITGA4 (0.56) | ITGA4ITGB1 | |
| SCHEMBL7389752 | 0.82 | ITGA4 (0.54) | ITGA4ITGB1ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |