Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 18/20 | 0.55 |
| ▸ | ITGB1 | P05556 | 17/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649470 | 0.91 | ITGB1 (0.52) | ITGA4ITGB1 | |
| SCHEMBL7645875 | 0.89 | ITGA4 (0.49) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7387358 | 0.88 | ITGA4 (0.62) | ITGA4ITGB1CHEK1 | |
| SCHEMBL7648766 | 0.88 | ITGA4 (0.56) | ITGA4ITGB1 | |
| SCHEMBL7425600 | 0.87 | ITGA4 (0.52) | ITGA4ITGB1CHEK1 | |
| SCHEMBL7424976 | 0.84 | ITGA4 (0.55) | ITGA4ITGB1CHEK1 | |
| SCHEMBL7588934 | 0.83 | ITGA4 (0.60) | ITGA4ITGB1CHEK1 | |
| SCHEMBL7420865 | 0.83 | ITGA4 (0.61) | ITGA4ITGB1CHEK1 | |
| SCHEMBL7561313 | 0.83 | ITGB1 (0.63) | ITGA4ITGB1CHEK1ITGB7 | |
| SCHEMBL7391722 | 0.82 | ITGB1 (0.57) | ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |