Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MAX | P61244 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816286 | 0.88 | KMT2A (0.54) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL7645879 | 0.86 | MAPT (0.51) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL6816304 | 0.80 | MTOR (0.59) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL7568344 | 0.80 | MEN1 (0.61) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL7571106 | 0.79 | MEN1 (0.52) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL7599105 | 0.77 | CDK1 (0.49) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL7645878 | 0.77 | MAOB (0.36) | MAPTKMT2ALMNAL3MBTL1NPSR1 | |
| SCHEMBL7639021 | 0.77 | MEN1 (0.52) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL6815197 | 0.76 | NAMPT (0.53) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL6816259 | 0.75 | MYC (0.68) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462055-B2 | VIRICIDES | WYETH | 2002-10-08 | — | — | US | disclosed |