Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | MAX | P61244 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816295 | 0.86 | MEN1 (0.58) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7645877 | 0.86 | ALDH1A1 (0.48) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7568351 | 0.78 | MAPT (0.67) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7571118 | 0.77 | CDK1 (0.53) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7639027 | 0.75 | CDK1 (0.53) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL6815204 | 0.74 | MEN1 (0.55) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL6816286 | 0.73 | KMT2A (0.54) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7638328 | 0.72 | EPHX1 (0.63) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7166829 | 0.72 | CDK1 (0.63) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL14631699 | 0.72 | POLB (0.39) | MAPTMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462055-B2 | VIRICIDES | WYETH | 2002-10-08 | — | — | US | disclosed |