Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | VNN1 | O95497 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.34 |
| ▸ | MLYCD | O95822 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816291 | 0.88 | KMT2A (0.40) | MAOBVNN1NPSR1MAP2K4EPHX2 | |
| SCHEMBL6816308 | 0.81 | MLYCD (0.50) | MAOBVNN1EPHX2NR1H4MLYCD | |
| SCHEMBL7568347 | 0.80 | MLYCD (0.54) | MAOBVNN1HDAC8HDAC6MLYCD | |
| SCHEMBL7571112 | 0.80 | TRPV1 (0.37) | MAOBNPSR1MAPTMAP2K4P2RY14 | |
| SCHEMBL7639025 | 0.77 | MAOB (0.38) | MAOBMAP2K4P2RY14MLYCD | |
| SCHEMBL7599109 | 0.77 | POLQ (0.41) | MAOBMAPTMAP2K4EPHX2 | |
| SCHEMBL7645877 | 0.77 | ALDH1A1 (0.48) | NPSR1MAPTXBP1P2RY14LMNA | |
| SCHEMBL6815202 | 0.77 | VNN1 (0.47) | MAOBVNN1EPHX2NR1H4MLYCD | |
| SCHEMBL7597480 | 0.75 | MLYCD (0.42) | MAOBVNN1EPHX2NR1H4MLYCD | |
| SCHEMBL7166826 | 0.75 | MAOB (0.47) | MAOBEPHX2NR1H4MLYCDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462055-B2 | VIRICIDES | WYETH | 2002-10-08 | — | — | US | disclosed |