Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELE | P16581 | 6/20 | 0.70 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 9/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053402 | 0.82 | ICAM1 (1.00) | SELEICAM1 | |
| SCHEMBL7053399 | 0.82 | ICAM1 (1.00) | SELEICAM1 | |
| SCHEMBL7052862 | 0.81 | SELE (0.81) | SELEICAM1 | |
| SCHEMBL7052854 | 0.81 | SELE (0.81) | SELEICAM1 | |
| SCHEMBL14375112 | 0.71 | RAB9A (0.70) | RAB9ANPC1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14441229 | 0.68 | RAB9A (0.70) | RAB9ANPC1L3MBTL1MEN1POLB | |
| SCHEMBL20866527 | 0.68 | RAB9A (0.81) | RAB9ANPC1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28341788 | 0.67 | RAB9A (0.68) | RAB9ANPC1L3MBTL1MEN1POLB | |
| SCHEMBL28341787 | 0.67 | RAB9A (0.68) | RAB9ANPC1L3MBTL1MEN1POLB | |
| SCHEMBL10458323 | 0.67 | RAB9A (1.00) | ICAM1RAB9ANPC1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181296-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | claimed |
| EP-1090009-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-04-11 | — | — | EP | claimed |
| WO-2000075145-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-12-14 | — | — | WO | claimed |
| WO-1999062908-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 1999-12-09 | — | — | WO | claimed |