Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL7645933 | 1.00 | ALDH1A1 (0.50) | ALDH1A1LMNAFOLH1ALOX15KDM4E | |
| SCHEMBL109681 | 0.93 | LMNA (0.55) | ALDH1A1LMNAFOLH1ALOX15KDM4E | |
| SCHEMBL109682 | 0.93 | LMNA (0.55) | ALDH1A1LMNAFOLH1ALOX15KDM4E | |
| SCHEMBL109680 | 0.93 | LMNA (0.55) | ALDH1A1LMNAFOLH1ALOX15KDM4E | |
| SCHEMBL1332039 | 0.93 | LMNA (0.55) | ALDH1A1LMNAFOLH1ALOX15KDM4E | |
| SCHEMBL11428360 | 0.91 | LMNA (0.54) | ALDH1A1LMNAFOLH1ALOX15KDM4E | |
| SCHEMBL2639626 | 0.91 | LMNA (0.54) | ALDH1A1LMNAFOLH1ALOX15KDM4E | |
| Selenium SCHEMBL13278146 | 0.91 | LMNA (0.54) | ALDH1A1LMNAFOLH1ALOX15KDM4E | |
| SCHEMBL2639625 | 0.91 | LMNA (0.54) | ALDH1A1LMNAFOLH1ALOX15KDM4E | |
| SCHEMBL28030829 | 0.91 | LMNA (0.54) | ALDH1A1LMNAFOLH1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482853-B1 | Lactate thiolester for cardiac energy resuscitation and prevention of reperfusion injury and use as an energy supplement during exercise and recovery | BROOKS GEORGE A (US) | 2002-11-19 | — | — | US | claimed |
| US-12023382-B2 | Molecules, formulations, and methods for nutritional support of athletes, patients, and others | Today Inc. (US) | 2024-07-02 | — | — | US | disclosed |
| WO-2023139357-A1 | MOLECULES, NUTRITIONAL FORMULATIONS, AND METHODS OF PROVIDING NUTRITIONAL SUPPORT | Today Inc. (US) | 2023-07-27 | — | — | WO | disclosed |
| US-20230226187-A1 | MOLECULES, FORMULATIONS, AND METHODS FOR NUTRITIONAL SUPPORT OF ATHLETES, PATIENTS, AND OTHERS | Today Inc. (US) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226187-A1 | MOLECULES, FORMULATIONS, AND METHODS FOR NUTRITIONAL SUPPORT OF ATHLETES, PATIENTS, AND OTHERS | CPT1B, GK, CPT1A | ALDH1A1 1249/4885LMNA 1973/4885FOLH1 3068/4885 |
| US-12023382-B2 | Molecules, formulations, and methods for nutritional support of athletes, patients, and others | CPT1B, GK, CPT1A | ALDH1A1 1249/4885LMNA 1973/4885FOLH1 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.