Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979938 | 1.00 | ALDH1A1 (0.44) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL7641536 | 1.00 | ALDH1A1 (0.44) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL983728 | 0.87 | ALDH1A1 (0.54) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL31650964 | 0.85 | ALDH1A1 (0.56) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL28452557 | 0.83 | ALDH1A1 (0.54) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL28541786 | 0.76 | TNKS (0.43) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL28541756 | 0.76 | ALDH1A1 (0.49) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL28542569 | 0.76 | KMT2A (0.47) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL28536177 | 0.73 | CA2 (0.42) | ALDH1A1CA2RAB9ASLC6A3KDM4E | |
| SCHEMBL14410146 | 0.73 | TSHR (0.47) | ALDH1A1KDM4EKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469133-B2 | SUCH AS CRYSTALLINE POLYLACTIDE AND POLYMANDELIDE, FROM SUBSTITUTED 1,4-DIOXAN-2,5-DIONES BY MIXING AN ANHYDROUS METAL ORGANIC LIGAND WITH THE DIOXANEDIONE AND HEATING; HIGH MELTING BIODEGRADABLE POLYMERS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2002-10-22 | — | — | US | disclosed |
| US-20010044514-A1 | Process for the preparation of polymers of dimeric cyclic esters | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2001-11-22 | — | — | US | disclosed |