Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646031 | 0.94 | SLC18A3 (0.36) | SLC18A3CYP3A4ALDH1A1CYP1A2LMNA | |
| SCHEMBL13210630 | 0.86 | DRD2 (0.38) | ALDH1A1LMNACYP2C9L3MBTL1DRD2 | |
| SCHEMBL19354324 | 0.84 | CYP1A2 (0.41) | SLC18A3ALDH1A1CYP1A2LMNAL3MBTL1 | |
| SCHEMBL22699060 | 0.84 | CYP1A2 (0.41) | SLC18A3ALDH1A1CYP1A2LMNAL3MBTL1 | |
| SCHEMBL11075113 | 0.81 | L3MBTL3 (0.40) | CYP3A4ALDH1A1LMNACYP2C9L3MBTL1 | |
| SCHEMBL11075108 | 0.81 | L3MBTL3 (0.40) | CYP3A4ALDH1A1LMNACYP2C9L3MBTL1 | |
| SCHEMBL17662672 | 0.75 | — | — | |
| SCHEMBL17662649 | 0.75 | — | — | |
| SCHEMBL14962056 | 0.75 | — | — | |
| SCHEMBL14253891 | 0.75 | CYP2D6 (0.33) | ALDH1A1CYP1A2LMNAL3MBTL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482837-B1 | Antimuscarinic compounds and methods for treatment of bladder diseases | UNIVERSITY OF ROCHESTER | 2002-11-19 | — | — | US | disclosed |