Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 9/20 | 0.74 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.74 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22223257 | 1.00 | GNAI3 (0.74) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL13097131 | 0.85 | GNAI3 (0.67) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL22223262 | 0.84 | GNAI3 (0.54) | GNAI3GNAI1GNAO1ITGB3ITGA2B | |
| SCHEMBL7399771 | 0.84 | GNAI3 (0.54) | GNAI3GNAI1GNAO1MEN1KMT2A | |
| SCHEMBL26038984 | 0.84 | GNAI3 (0.68) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL16072734 | 0.84 | GNAI3 (0.68) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL16072733 | 0.84 | GNAI3 (0.68) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL13773022 | 0.83 | GNAI3 (0.68) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL7407892 | 0.83 | GNAI3 (0.51) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL754482 | 0.82 | GNAI3 (0.67) | GNAI3GNAI1GNAO1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2842576-B1 | Transglutaminase mediated conjugation of peptides | NOVO NORDISK HEALTHCARE AG (CH) | 2017-06-28 | — | — | EP | disclosed |
| EP-2842576-A1 | Transglutaminase mediated conjugation of peptides | Novo Nordisk Health Care AG (CH) | 2015-03-04 | — | — | EP | disclosed |
| EP-2033662-B1 | Transglutaminase mediated conjugation of peptides | NOVO NORDISK HEALTHCARE AG (CH) | 2012-10-17 | — | — | EP | disclosed |
| EP-1708755-B1 | TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES | NOVO NORDISK HEALTHCARE AG (CH) | 2012-03-21 | — | — | EP | disclosed |
| EP-2368579-A1 | Transglutaminase mediated conjugation of peptides | Novo Nordisk Health Care AG (CH) | 2011-09-28 | — | — | EP | disclosed |
| EP-2033662-A1 | Transglutaminase mediated conjugation of peptides | Novo Nordisk Health Care AG (CH) | 2009-03-11 | — | — | EP | disclosed |
| EP-0195016-A1 | CYCLIMMONIUM SALTS | SANDOZ AG (CH) | 1986-09-24 | — | — | EP | disclosed |
| WO-1986001507-A1 | CYCLIMMONIUM SALTS | SANDOZ AG (CH) | 1986-03-13 | — | — | WO | disclosed |