Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 8/20 | 0.54 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.54 |
| ▸ | GNAI1 | P63096 | 8/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407892 | 0.98 | GNAI3 (0.51) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL764605 | 0.84 | GNAI3 (0.74) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL22223262 | 0.84 | GNAI3 (0.54) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL22223257 | 0.84 | GNAI3 (0.74) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7475020 | 0.79 | GNAI3 (0.51) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL22223259 | 0.79 | GNAI3 (0.48) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL7444832 | 0.78 | GNAI3 (0.50) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL7396649 | 0.77 | HDAC6 (0.53) | ITGB3ITGA2BNPC1KDM4EMEN1 | |
| SCHEMBL7398844 | 0.77 | HDAC6 (0.53) | ITGB3ITGA2BNPC1KDM4EMEN1 | |
| SCHEMBL7401338 | 0.77 | HDAC6 (0.53) | ITGB3ITGA2BNPC1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024390-A1 | NOVEL PHENYL(-ALKYL/ALKOXY)-1-AMINOALKYL-SUBSTITUTED PIPERIDINES AND PYRROLIDINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-09-14 | — | — | WO | disclosed |