Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 8/20 | 0.75 |
| ▸ | KRAS | P01116 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MPO | P05164 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27798635 | 1.00 | SOS1 (0.75) | SOS1KRASKMT2AMEN1LMNA | |
| SCHEMBL9825896 | 1.00 | SOS1 (0.75) | SOS1KRASKMT2AMEN1LMNA | |
| SCHEMBL7649209 | 0.94 | SOS1 (0.80) | SOS1KRASKMT2AMEN1LMNA | |
| SCHEMBL27798619 | 0.94 | SOS1 (0.80) | SOS1KRASKMT2AMEN1LMNA | |
| SCHEMBL7623409 | 0.86 | SOS1 (0.69) | SOS1KRASKMT2AMEN1LMNA | |
| SCHEMBL7675962 | 0.86 | MMP2 (0.63) | SOS1KRASKMT2AMEN1LMNA | |
| SCHEMBL20805200 | 0.86 | SOS1 (1.00) | SOS1KRAS | |
| SCHEMBL28799369 | 0.84 | SOS1 (0.56) | SOS1KRASKMT2AMEN1LMNA | |
| SCHEMBL28799370 | 0.84 | SOS1 (0.56) | SOS1KRASKMT2AMEN1LMNA | |
| SCHEMBL21841550 | 0.82 | SOS1 (0.63) | SOS1KRASKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101932560-A | Matrix metalloproteinase inhibitors, pharmaceutical compositions containing them and their use | POISON MED INST PLA MED ACAD | 2010-12-29 | — | — | CN | disclosed |
| US-6475985-B1 | Nucleosides with antiviral and anticancer activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-11-05 | — | — | US | disclosed |
| WO-1999049873-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1999-10-07 | — | — | WO | disclosed |