Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645771 | 0.89 | MAPT (0.43) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL6935668 | 0.82 | MAPT (0.44) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL6999972 | 0.82 | MALT1 (0.39) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL7234618 | 0.82 | MAPT (0.50) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL7441422 | 0.81 | MDM2 (0.41) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL7002338 | 0.81 | MAPT (0.41) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL7000840 | 0.80 | MAPT (0.41) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL6933786 | 0.75 | PSD (0.44) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL6997430 | 0.74 | GRIA2 (0.46) | MAPTMEN1KMT2AMAPK1RAB9A | |
| SCHEMBL6993558 | 0.74 | MAPT (0.41) | MAPTMEN1KMT2AMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482819-B1 | 2,3-benzodiazepine derivatives | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2002-11-19 | — | — | US | disclosed |