Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PSD | A5PKW4 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933786 | 0.93 | PSD (0.44) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL6935103 | 0.89 | MAPT (0.44) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL6937957 | 0.85 | MAPT (0.44) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL7000840 | 0.85 | MAPT (0.41) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL2001951 | 0.85 | ALDH1A1 (0.39) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL7498251 | 0.84 | KMT2A (0.44) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL7609618 | 0.84 | APP (0.43) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL7002338 | 0.83 | MAPT (0.41) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL7645771 | 0.82 | MAPT (0.43) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL7646167 | 0.82 | MAPT (0.43) | MAPTMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802195-B1 | Substituted 2,3-benzodiazepine derivatives, process and intermediates for their preparation and pharmaceutical compositions comprising them as well as their use | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2003-11-19 | — | — | EP | disclosed |
| EP-1001956-B1 | 2,3-BENZODIAZEPINE DERIVATIVES | GYOGYSZERKUTATO INTEZET (HU) | 2003-05-07 | — | — | EP | disclosed |
| US-6482819-B1 | 2,3-benzodiazepine derivatives | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2002-11-19 | — | — | US | disclosed |
| EP-1001956-A1 | NEW 2,3-BENZODIAZEPINE DERIVATIVES | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006408-A1 | NEW 2,3-BENZODIAZEPINE DERIVATIVES | Gyógyszerkutató Intézet Kft. (HU) | 1999-02-11 | — | — | WO | disclosed |
| US-5807851-A | MUSCLE RELAXANTS; NERVOUS SYSTEM DISORDERS | EGIS GYOGYSZERGYAR RT. (HU) | 1998-09-15 | — | — | US | disclosed |
| EP-0802195-A2 | Substituted 2,3-benzodiazepine derivatives, process and intermediates for their preparation and pharmaceutical compositions comprising them as well as their use | EGIS GYOGYSZERGYAR RT. (HU) | 1997-10-22 | — | — | EP | disclosed |