Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 7/20 | 0.68 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.55 |
| ▸ | ESR1 | P03372 | 7/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29379733 | 0.98 | HSD17B1 (0.70) | HSD17B1HSD17B2ALOX5ESR2ESR1 | |
| SCHEMBL2399731 | 0.98 | HSD17B1 (0.70) | HSD17B1HSD17B2ALOX5ESR2ESR1 | |
| SCHEMBL503208 | 0.98 | HSD17B1 (0.70) | HSD17B1HSD17B2ALOX5ESR2ESR1 | |
| SCHEMBL29429122 | 0.98 | HSD17B1 (0.70) | HSD17B1HSD17B2ALOX5ESR2ESR1 | |
| SCHEMBL31574436 | 0.93 | HSD17B1 (0.66) | HSD17B1HSD17B2ALOX5ESR2ESR1 | |
| SCHEMBL31574433 | 0.93 | HSD17B1 (0.66) | HSD17B1HSD17B2ALOX5ESR2ESR1 | |
| SCHEMBL3811825 | 0.91 | HSD17B1 (0.72) | HSD17B1HSD17B2ALOX5ESR2ESR1 | |
| Hydrogen Sulfide SCHEMBL22042810 | 0.91 | HSD17B1 (0.65) | HSD17B1HSD17B2ESR2ESR1TP53 | |
| SCHEMBL13589555 | 0.91 | HSD17B1 (0.72) | HSD17B1HSD17B2ALOX5ESR2ESR1 | |
| Hydrogen Sulfide SCHEMBL6269773 | 0.91 | HSD17B1 (0.65) | HSD17B1HSD17B2ESR2ESR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020182279-A1 | Melt drip pelletization of polycarbonate oligomers and polymers | GENERAL ELECTRIC COMPANY | 2002-12-05 | — | — | US | disclosed |