SCHEMBL503208

SCHEMBL503208

Cc1cc(-c2ccc(-c3ccc(O)cc3)cc2)ccc1O

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 7/20 0.70
HSD17B2 P37059 7/20 0.70
ALOX5 P09917 1/20 0.62
ESR2 Q92731 6/20 0.57
ESR1 P03372 7/20 0.55
TP53 P04637 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
TLR8 Q9NR97 1/20 0.51
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29429122 1.00 HSD17B1 (0.70) HSD17B1HSD17B2ALOX5ESR2ESR1
SCHEMBL2399731 1.00 HSD17B1 (0.70) HSD17B1HSD17B2ALOX5ESR2ESR1
SCHEMBL29379733 1.00 HSD17B1 (0.70) HSD17B1HSD17B2ALOX5ESR2ESR1
Hydrogen Sulfide SCHEMBL7646232 0.98 HSD17B1 (0.68) HSD17B1HSD17B2ALOX5ESR2ESR1
SCHEMBL31574433 0.96 HSD17B1 (0.66) HSD17B1HSD17B2ALOX5ESR2ESR1
SCHEMBL31574436 0.96 HSD17B1 (0.66) HSD17B1HSD17B2ALOX5ESR2ESR1
SCHEMBL3811825 0.93 HSD17B1 (0.72) HSD17B1HSD17B2ALOX5ESR2ESR1
SCHEMBL13589555 0.93 HSD17B1 (0.72) HSD17B1HSD17B2ALOX5ESR2ESR1
Methylhydroquinone SCHEMBL5712106 0.91 HSD17B1 (0.64) HSD17B1HSD17B2ALOX5ESR2ESR1
SCHEMBL272034 0.90 HSD17B1 (0.68) HSD17B1HSD17B2ESR2ESR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1375461-B1 DIPHENOL AND PROCESS FOR PRODUCING THE SAME HONSHU CHEMICAL IND (JP) 2009-08-05 EP claimed
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2026-03-05 US disclosed
US-12460099-B2 Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment THE PILOT INK CO., LTD. (JP) 2025-11-04 US disclosed
US-12421411-B2 Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument KABUSHIKI KAISHA PILOT CORPORATION (JP) 2025-09-23 US disclosed
CN-118339201-A Vinyl compound, method for producing vinyl compound, vinyl composition, vinyl resin cured product, prepreg, resin-coated film, resin-coated metal foil, metal-clad laminate, and printed wiring board 住友化学株式会社 2024-07-12 CN disclosed
US-20230331925-A1 THERMOPLASTIC RESIN, COMPOSITION, MOLDED ARTICLE, OPTICAL LENS, AND METHOD FOR PRODUCING THERMOPLASTIC RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-10-19 US disclosed
EP-4219589-A1 THERMOPLASTIC RESIN, COMPOSITION, MOLDED ARTICLE, OPTICAL LENS, AND METHOD FOR PRODUCING THERMOPLASTIC RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-08-02 EP disclosed
WO-2023106052-A1 VINYL COMPOUND, METHOD FOR PRODUCING VINYL COMPOUND, VINYL COMPOSITION, VINYL RESIN CURED PRODUCT, PREPREG, FILM WITH RESIN, METAL FOIL WITH RESIN, METAL-CLAD LAMINATE AND PRINTED WIRING BOARD 住友化学株式会社 2023-06-15 WO disclosed
US-20230018132-A1 REVERSIBLY THERMOCHROMIC AQUEOUS INKJET PRINTER INK COMPOSITION, INKJET PRINTER AND INK CARTRIDGE USING THE SAME RISO TECHNOLOGIES CORPORATION (JP) 2023-01-19 US disclosed
US-20220251406-A1 AQUEOUS INK COMPOSITION FOR REVERSIBLY THERMOCHROMIC WRITING INSTRUMENT, AND REFILL AND AQUEOUS BALLPOINT PEN INCORPORATING AQUEOUS INK COMPOSITION FOR REVERSIBLY THERMOCHROMIC WRITING INSTRUMENT KABUSHIKI KAISHA PILOT CORPORATION (ALSO TRADING AS PILOT CORPORATION) (JP) 2022-08-11 US disclosed
US-7538166-B2 Epoxy compounds and cured epoxy resins obtained by curing the compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-26 US disclosed
CN-101400665-A Method for producing epoxy compound SUMITOMO CHEMICAL CO (JP) 2009-04-01 CN disclosed
US-20090054669-A1 Process For Producing Epoxy Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-26 US disclosed
EP-1995245-A1 METHOD FOR PRODUCING EPOXY COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-11-26 EP disclosed
US-20070184280-A1 Epoxy compounds and cured epoxy resins obtained by curing the compounds HITACHI, LTD. (JP) 2007-08-09 US disclosed
CN-1898223-A Epoxy compound and epoxy resin cured product obtained by curing the epoxy compound SUMITOMO CHEMICAL CO (JP) 2007-01-17 CN disclosed
EP-1698625-A1 EPOXY COMPOUNDS AND CURED EPOXY RESINS OBTAINED BY CURING THE COMPOUNDS Sumitomo Chemical Company, Limited (JP) 2006-09-06 EP disclosed
US-6872858-B2 Diphenol and process for producing the same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2005-03-29 US disclosed
US-20040049086-A1 Diphenol and process for producing the same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2004-03-11 US disclosed
EP-1375461-A1 DIPHENOL AND PROCESS FOR PRODUCING THE SAME Honshu Chemical Industry Co. Ltd. (JP) 2004-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT TYR, SCO2, HBB HSD17B1 1523/4885HSD17B2 1361/4885ALOX5 862/4885
US-20090054669-A1 Process For Producing Epoxy Compound RER1, AR, CYP1A1 HSD17B1 64/4885HSD17B2 47/4885ALOX5 609/4885
US-20040049086-A1 Diphenol and process for producing the same CYP1A1, AHR, CYP2E1 HSD17B1 65/4885HSD17B2 139/4885ALOX5 907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.