Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 6/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1882703 | 0.90 | CYP2C9 (0.37) | ADRB2CYP2C9MEN1CYP2D6CYP2C19 | |
| SCHEMBL1881772 | 0.79 | GABBR2 (0.54) | CYP2C9MEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL390483 | 0.76 | ADRB2 (0.43) | ADRB2CYP2C9MEN1CYP2D6CYP2C19 | |
| SCHEMBL391358 | 0.75 | ADRB2 (0.46) | ADRB2CYP2C9MEN1CYP2D6CYP2C19 | |
| SCHEMBL16649881 | 0.75 | ADRB2 (0.46) | ADRB2CYP2C9MEN1CYP2D6CYP2C19 | |
| SCHEMBL390400 | 0.75 | ADRB2 (0.46) | ADRB2CYP2C9MEN1CYP2D6CYP2C19 | |
| SCHEMBL16649759 | 0.74 | SLC6A4 (0.50) | ADRB2CYP2C9MEN1CYP2D6CYP2C19 | |
| SCHEMBL1534396 | 0.74 | SLC6A4 (0.50) | ADRB2CYP2C9MEN1CYP2D6CYP2C19 | |
| SCHEMBL3834911 | 0.73 | CYP2C9 (0.51) | ADRB2CYP2C9MEN1CYP2D6CYP2C19 | |
| SCHEMBL3834914 | 0.73 | CYP2C9 (0.51) | ADRB2CYP2C9MEN1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | claimed |
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | disclosed |