Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528666 | 0.87 | SNCA (0.47) | ALDH1A1PKMSNCAKMT2AMAPT | |
| SCHEMBL7528656 | 0.87 | SNCA (0.47) | ALDH1A1PKMSNCAKMT2AMAPT | |
| SCHEMBL7644888 | 0.83 | PTPN1 (0.46) | ALDH1A1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL7530317 | 0.79 | KCNK2 (0.47) | ALDH1A1SNCAKMT2ALMNAMAPT | |
| SCHEMBL7530325 | 0.79 | KCNK2 (0.47) | ALDH1A1SNCAKMT2ALMNAMAPT | |
| SCHEMBL7523894 | 0.79 | PTPN1 (0.48) | KMT2AMAPTPTPN1HNF4ASMN1; SMN2 | |
| SCHEMBL7523907 | 0.79 | PTPN1 (0.48) | KMT2AMAPTPTPN1HNF4ASMN1; SMN2 | |
| SCHEMBL7527364 | 0.77 | MAPT (0.57) | ALDH1A1KDM4EPKMSNCAKMT2A | |
| SCHEMBL7527352 | 0.77 | MAPT (0.57) | ALDH1A1KDM4EPKMSNCAKMT2A | |
| SCHEMBL7526855 | 0.77 | SNCA (0.47) | ALDH1A1PKMSNCAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |