Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.48 |
| ▸ | HNF4A | P41235 | 1/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523894 | 1.00 | PTPN1 (0.48) | PTPN1HNF4ASRD5A1SRD5A2CASP3 | |
| SCHEMBL7531126 | 0.84 | PTPN1 (0.63) | PTPN1HNF4APTPN6PTPN2RARA | |
| SCHEMBL7531117 | 0.84 | PTPN1 (0.63) | PTPN1HNF4APTPN6PTPN2RARA | |
| SCHEMBL7528656 | 0.83 | SNCA (0.47) | PTPN1HNF4ASRD5A1SRD5A2KMT2A | |
| SCHEMBL7528666 | 0.83 | SNCA (0.47) | PTPN1HNF4ASRD5A1SRD5A2KMT2A | |
| SCHEMBL7523901 | 0.80 | PTPN1 (0.47) | PTPN1HNF4ASRD5A1SRD5A2CASP3 | |
| SCHEMBL7646353 | 0.80 | PTPN1 (0.40) | PTPN1HNF4ASRD5A1SRD5A2CASP3 | |
| SCHEMBL7646355 | 0.79 | ALDH1A1 (0.47) | PTPN1HNF4AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7530268 | 0.78 | APP (0.40) | PTPN1HNF4ACASP3KMT2ASENP8 | |
| SCHEMBL7530259 | 0.78 | APP (0.40) | PTPN1HNF4ACASP3KMT2ASENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | TELIK, INC. | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | SLC2A1, SLC2A8, SLC2A2 | PTPN1 1380/4885HNF4A 425/4885SRD5A1 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.