Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 3/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646372 | 1.00 | GABRR1 (0.41) | GABRR1GSRRNPEPCPB2LMNA | |
| SCHEMBL3421975 | 0.86 | GABRR1 (0.44) | GABRR1GSRRNPEPSLC7A5 | |
| SCHEMBL31040415 | 0.86 | PAOX (0.45) | LMNAKMT2ACYP1A2TSHRHDAC6 | |
| SCHEMBL13165158 | 0.81 | GABRR1 (0.40) | GABRR1GSRRNPEPCPB2LMNA | |
| SCHEMBL28856644 | 0.80 | MMP1 (0.42) | TSHRHDAC1HDAC2ALDH1A1SLC6A3 | |
| SCHEMBL28856645 | 0.80 | MMP1 (0.42) | TSHRHDAC1HDAC2ALDH1A1SLC6A3 | |
| SCHEMBL8524074 | 0.78 | ACE2 (0.42) | KMT2ATSHRHDAC11MEN1ALDH1A1 | |
| SCHEMBL10973416 | 0.78 | ACE2 (0.42) | KMT2ATSHRHDAC11MEN1ALDH1A1 | |
| SCHEMBL8523775 | 0.78 | ACE2 (0.42) | KMT2ATSHRHDAC11MEN1ALDH1A1 | |
| SCHEMBL30099776 | 0.78 | GABRR1 (0.38) | GABRR1GSRLMNATHRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455626-B2 | SOFTNESS, HIGH DAMPING | BRIDGESTONE CORPORATION (JP) | 2002-09-24 | — | — | US | claimed |
| US-20010034393-A1 | Gels derived from extending grafted centipede polymers and polypropylene | WANG XIAORONG (US) | 2001-10-25 | — | — | US | claimed |