Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.33 |
| ▸ | CDK2 | P24941 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648501 | 0.78 | MAPT (0.43) | GAAMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL3237315 | 0.73 | GAA (0.53) | GAAMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL11498206 | 0.68 | GAA (0.46) | GAAMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL11779167 | 0.67 | ALDH1A1 (0.59) | GAAMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL9405274 | 0.65 | — | — | |
| SCHEMBL11069846 | 0.64 | — | — | |
| SCHEMBL11069840 | 0.64 | — | — | |
| SCHEMBL23808297 | 0.64 | GBA1 (0.46) | GAAMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL276285 | 0.64 | GAA (0.46) | GAAMAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL11195162 | 0.64 | GAA (0.46) | GAAMAPTSMN1; SMN2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020002171-A1 | Materials and methods for killing nematodes and nematode eggs | AKKADIX CORPORATION | 2002-01-03 | — | — | US | disclosed |
| WO-2001054506-A1 | METHODS FOR KILLING NEMATODES AND NEMATODE EGGS USING BIS-AMINO-1,2,4-THIADIAZOLES | AKKADIX CORPORATION (US) | 2001-08-02 | — | — | WO | disclosed |