Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.36 |
| ▸ | CDK2 | P24941 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646647 | 0.78 | GAA (0.39) | MAPTSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL20876859 | 0.77 | CCNA2 (0.38) | MAPTSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL20321948 | 0.74 | — | — | |
| SCHEMBL25083683 | 0.74 | — | — | |
| SCHEMBL25083679 | 0.71 | KMT2A (0.40) | MAPTKMT2ACYP1A2CYP2C19MEN1 | |
| SCHEMBL24256370 | 0.69 | ESR1 (0.47) | SMN1; SMN2 | |
| SCHEMBL3414696 | 0.67 | KMT2A (0.57) | MAPTSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL4856408 | 0.67 | KMT2A (0.61) | MAPTKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11576217 | 0.67 | ALDH1A1 (0.51) | MAPTSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL24725742 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020002171-A1 | Materials and methods for killing nematodes and nematode eggs | AKKADIX CORPORATION | 2002-01-03 | — | — | US | disclosed |
| WO-2001054506-A1 | METHODS FOR KILLING NEMATODES AND NEMATODE EGGS USING BIS-AMINO-1,2,4-THIADIAZOLES | AKKADIX CORPORATION (US) | 2001-08-02 | — | — | WO | disclosed |