Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 19/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 18/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 18/20 | 0.38 |
| ▸ | GABRP | O00591 | 16/20 | 0.38 |
| ▸ | GABRD | O14764 | 16/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 16/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 16/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 16/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 16/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 16/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 16/20 | 0.38 |
| ▸ | GABRE | P78334 | 16/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 16/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 16/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 16/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 16/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7249122 | 0.86 | GABRP (0.47) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10425168 | 0.82 | GABRB3 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7025824 | 0.80 | GABRB3 (0.38) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7027748 | 0.79 | GABRP (0.47) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7029619 | 0.79 | GABRP (0.47) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL1408607 | 0.78 | GABRB3 (0.48) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7250317 | 0.77 | GABRP (0.44) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL8531723 | 0.76 | GABRB3 (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7032123 | 0.76 | GABRP (0.44) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10425080 | 0.74 | GABRB3 (0.42) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879229-B1 | ARYLPYRAZOLE INSECTICIDES | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-6316477-B1 | NO DAMAGE TO PLANTS, LESS TOXIC TO FISH | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-11-13 | — | — | US | disclosed |