Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680232 | 1.00 | LMNA (0.38) | LMNAL3MBTL1PDE4ATDP1KDM4E | |
| SCHEMBL8720966 | 1.00 | LMNA (0.38) | LMNAL3MBTL1PDE4ATDP1KDM4E | |
| SCHEMBL7552449 | 1.00 | LMNA (0.38) | LMNAL3MBTL1PDE4ATDP1KDM4E | |
| SCHEMBL27949628 | 1.00 | LMNA (0.38) | LMNAL3MBTL1PDE4ATDP1KDM4E | |
| SCHEMBL28231713 | 0.84 | LMNA (0.48) | LMNAL3MBTL1PDE4ATDP1KDM4E | |
| SCHEMBL7525631 | 0.84 | LMNA (0.48) | LMNAL3MBTL1PDE4ATDP1KDM4E | |
| SCHEMBL8718440 | 0.84 | LMNA (0.48) | LMNAL3MBTL1PDE4ATDP1KDM4E | |
| SCHEMBL4744871 | 0.84 | LMNA (0.48) | LMNAL3MBTL1PDE4ATDP1KDM4E | |
| SCHEMBL8722914 | 0.82 | PDE4A (0.54) | LMNAL3MBTL1PDE4ATDP1KDM4E | |
| SCHEMBL8718317 | 0.82 | PDE4A (0.54) | LMNAL3MBTL1PDE4ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224190-A1 | SUBSTITUTED DIBORON COMPOUNDS | Commonwealth Scientific and Research Organisation (AU) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001029051-A1 | SUBSTITUTED DIBORON COMPOUNDS | COMMONWEALTH SCIENTIFIC AND RESEARCH ORGANISATION (AU) | 2001-04-26 | — | — | WO | disclosed |
| EP-0600020-B1 | ASYMMETRIC SYNTHESES | UNION CARBIDE CHEM PLASTIC (US) | 1996-01-31 | — | — | EP | disclosed |
| EP-0558656-A1 | NEW METHODS FOR THE CATALYTIC REDUCTION OF ORGANIC SUBSTRATES. | MASSACHUSETTS INST TECHNOLOGY (US) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992009545-A2 | NEW METHODS FOR THE CATALYTIC REDUCTION OF ORGANIC SUBSTRATES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1992-06-11 | — | — | WO | disclosed |