Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | OTC | P00480 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26605993 | 0.83 | TSHR (0.48) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL10938189 | 0.81 | KDM4E (0.38) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL328930 | 0.81 | TSHR (0.33) | — | |
| SCHEMBL9192261 | 0.80 | KDM4E (0.33) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| Medronic Acid SCHEMBL2587369 | 0.79 | KDM4E (0.62) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL1562522 | 0.77 | KDM4E (0.50) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL6525264 | 0.76 | KDM4E (0.33) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL14827466 | 0.73 | — | — | |
| SCHEMBL5591 | 0.72 | TSHR (0.55) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL14827470 | 0.72 | PPARD (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997098-A1 | CANNABINOID DERIVATIVES | Canopy Growth Corporation (CA) | 2022-05-18 | — | — | EP | claimed |
| WO-2021007662-A1 | CANNABINOID DERIVATIVES | CANOPY GROWTH CORPORATION (CA) | 2021-01-21 | — | — | WO | claimed |
| CN-108697719-B | Modulators of extracellular 5' -nucleotidases and uses thereof | 艾库斯生物科学有限公司 | 2024-03-19 | — | — | CN | disclosed |
| EP-4306525-A2 | MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF | Arcus Biosciences, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| EP-3399984-B1 | MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF | ARCUS BIOSCIENCES INC (US) | 2023-09-06 | — | — | EP | disclosed |
| US-11667662-B2 | Modulators of 5′-nucleotidase, ecto and the use thereof | ARCUS BIOSCIENCES, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-20220204539-A1 | CD73 INHIBITORS | BIOARDIS LLC | 2022-06-30 | — | — | US | disclosed |
| EP-3997098-A1 | CANNABINOID DERIVATIVES | Canopy Growth Corporation (CA) | 2022-05-18 | — | — | EP | disclosed |
| CN-114395005-A | Modulators of extracellular 5' -nucleotidase and uses thereof | 艾库斯生物科学有限公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-114286824-A | CD73 inhibitor | 博奥阿迪斯生物科技公司 | 2022-04-05 | — | — | CN | disclosed |
| US-20210371449-A1 | MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF | ARCUS BIOSCIENCES, INC. | 2021-12-02 | — | — | US | disclosed |
| US-20210002322-A1 | MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF | ARCUS BIOSCIENCES, INC. | 2021-01-07 | — | — | US | disclosed |
| US-20190309010-A1 | MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF | ARCUS BIOSCIENCES, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10239912-B2 | Modulators of 5′-nucleotidase, ecto and the use thereof | ARCUS BIOSCIENCES, INC. (US) | 2019-03-26 | — | — | US | disclosed |
| EP-3399984-A1 | MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF | Arcus Biosciences, Inc. (US) | 2018-11-14 | — | — | EP | disclosed |
| US-10093688-B2 | Non-aqueous liquid electrolyte, electricity storage device using same, and phosphorus compound used therein | UBE INDUSTRIES, LTD. (JP) | 2018-10-09 | — | — | US | disclosed |
| US-20170275311-A1 | NON-AQUEOUS LIQUID ELECTROLYTE, ELECTRICITY STORAGE DEVICE USING SAME, AND PHOSPHORUS COMPOUND USED THEREIN | UBE INDUSTRIES, LTD. (JP) | 2017-09-28 | — | — | US | disclosed |
| US-20170267710-A1 | MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF | ARCUS BIOSCIENCES, INC. | 2017-09-21 | — | — | US | disclosed |
| WO-2017120508-A1 | MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2017-07-13 | — | — | WO | disclosed |
| WO-2002085918-A1 | A FACILE SYNTHESIS OF SYMMETRIC ESTERS OF ALKYLENEBISPHOSPHONIC ACIDS | LOYOLA UNIVERSITY OF CHICAGO (US) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002322-A1 | MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF | ENTPD5, NT5C2, NT5E | KDM4E 2414/4885MMP2 1909/4885THRB 2386/4885 |
| US-20170267710-A1 | MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF | ENTPD5, NT5C2, NT5E | KDM4E 2414/4885MMP2 1909/4885THRB 2386/4885 |
| US-20210371449-A1 | MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF | ENTPD5, NT5C2, NT5E | KDM4E 2414/4885MMP2 1909/4885THRB 2386/4885 |
| US-20190309010-A1 | MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF | ENTPD5, NT5C2, NT5E | KDM4E 2414/4885MMP2 1909/4885THRB 2386/4885 |
| US-20220204539-A1 | CD73 INHIBITORS | ENTPD5, ENTPD1, ENTPD2 | KDM4E 1974/4885MMP2 526/4885THRB 2219/4885 |
| US-20170275311-A1 | NON-AQUEOUS LIQUID ELECTROLYTE, ELECTRICITY STORAGE DEVICE USING SAME, AND PHOSPHORUS COMPOUND USED THEREIN | SCN10A, CACNA2D4, P2RY10 | KDM4E 1583/4885MMP2 4266/4885THRB 4234/4885 |
| US-11667662-B2 | Modulators of 5′-nucleotidase, ecto and the use thereof | ENTPD5, NT5C2, NT5E | KDM4E 2438/4885MMP2 1888/4885THRB 2290/4885 |
| US-10239912-B2 | Modulators of 5′-nucleotidase, ecto and the use thereof | ENTPD5, NT5C2, NT5E | KDM4E 2438/4885MMP2 1888/4885THRB 2290/4885 |
| US-10093688-B2 | Non-aqueous liquid electrolyte, electricity storage device using same, and phosphorus compound used therein | SCN10A, CACNA2D4, P2RY10 | KDM4E 1765/4885MMP2 4505/4885THRB 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.