Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623221 | 0.78 | — | — | |
| SCHEMBL27769875 | 0.78 | TSHR (0.41) | — | |
| SCHEMBL7647258 | 0.76 | KDM4E (0.50) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL11325232 | 0.76 | — | — | |
| SCHEMBL26605993 | 0.75 | TSHR (0.48) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL2358290 | 0.75 | FNTA (0.46) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL4957358 | 0.75 | — | — | |
| SCHEMBL17331087 | 0.74 | ALDH1A1 (0.37) | HSD17B10 | |
| SCHEMBL2358289 | 0.74 | LPAR2 (0.31) | LPAR2LPAR3 | |
| SCHEMBL9055105 | 0.74 | LPAR2 (0.34) | FNTAFNTBLPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6909010-B2 | Facile synthesis of symmetric esters of alkylenebisphosphonic acids | LOYOLA UNIVERSITY OF CHICAGO (US) | 2005-06-21 | — | — | US | disclosed |
| US-20030060648-A1 | Facile synthesis of symmetric esters of alkylenebisphosphonic acids | LOYOLA UNIVERSITY OF CHICAGO | 2003-03-27 | — | — | US | disclosed |
| WO-2002085918-A1 | A FACILE SYNTHESIS OF SYMMETRIC ESTERS OF ALKYLENEBISPHOSPHONIC ACIDS | LOYOLA UNIVERSITY OF CHICAGO (US) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030060648-A1 | Facile synthesis of symmetric esters of alkylenebisphosphonic acids | PHOSPHO1, ADH1C, PAICS | KDM4E 3463/4885MMP2 3502/4885THRB 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.