SCHEMBL7647274

SCHEMBL7647274

Cc1cc(C)c(C(=O)P(=O)(O)c2ccccc2)c(C)c1.[MgH2]

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.40
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA5A P35218 1/20 0.39
LMNA P02545 3/20 0.38
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 2/20 0.35
ACP3 P15309 1/20 0.35
NPC1 O15118 1/20 0.35
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL117062 0.98 CFTR (0.41) CFTRCA2CA4CA5ALMNA
Lithium SCHEMBL29525491 0.97 CFTR (0.40) CFTRCA2CA4CA5ALMNA
SCHEMBL28569551 0.97 CFTR (0.40) CFTRCA2CA4CA5ALMNA
SCHEMBL12813050 0.97 CFTR (0.40) CFTRCA2CA4CA5ALMNA
Methoxymethane SCHEMBL29366991 0.94 POLB (0.38) CFTRCA2CA4CA5ALMNA
Hypophosphorous Acid SCHEMBL30987241 0.92 CFTR (0.37) CFTRCA2CA4CA5ALMNA
SCHEMBL28390844 0.91 CFTR (0.36) CFTRCA2CA4CA5ALMNA
P-Cresol SCHEMBL8938995 0.90 ESR1 (0.44) CFTRLMNAKMT2ASMN1; SMN2HTT
SCHEMBL16705220 0.88 LMNA (0.38) CFTRCA2CA4CA5ALMNA
Glycerin SCHEMBL23629558 0.87 LMNA (0.38) CFTRLMNAKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3837373-B1 HIGH THROUGHPUT CLONING OF PAIRED BIPARTITE IMMUNORECEPTOR POLYNUCLEOTIDES AND APPLICATIONS THEREOF ROOTPATH GENOMICS INC (US) 2024-06-12 EP disclosed
EP-4363225-A1 METHODS AND COMPOSITIONS COMPRISING CHAIN TRANSFER AGENTS IN ABSORBABLE PHOTOPOLYMERIZABLE FORMULATIONS Poly-Med Inc. (US) 2024-05-08 EP disclosed
EP-4257628-A2 METHODS AND COMPOSITIONS FOR PHOTOPOLYMERIZABLE ADDITIVE MANUFACTURING Poly-Med, Inc. (US) 2023-10-11 EP disclosed
US-20230287171-A1 MACROMERS AND COMPOSITIONS FOR PHOTOCURING PROCESSES POLY-MED, INC. 2023-09-14 US disclosed
US-20230272340-A1 COMPOSITIONS AND METHODS FOR ANTIGEN IDENTIFICATION ROOTPATH GENOMICS INC (US) 2023-08-31 US disclosed
EP-3774338-B1 METHODS AND COMPOSITIONS FOR PHOTOPOLYMERIZABLE ADDITIVE MANUFACTURING POLY MED INC (US) 2023-07-05 EP disclosed
EP-4196134-A1 COMPOSITIONS AND METHODS FOR ANTIGEN IDENTIFICATION Rootpath Genomics, Inc. (US) 2023-06-21 EP disclosed
US-20230183408-A1 CURABLE POLYMERIC COMPOSITIONS POLY-MED, INC. 2023-06-15 US disclosed
US-11639416-B2 Macromers and compositions for photocuring processes POLY-MED, INC. (US) 2023-05-02 US disclosed
CN-112840031-B High throughput cloning and use of paired bipartite immunoreceptor polynucleotides 根路径基因组学公司 2023-03-24 CN disclosed
EP-2960306-B1 Aqueous radiation curable inkjet inks AGFA NV (BE) 2020-12-23 EP disclosed
US-20200385785-A1 COMPOSITIONS AND METHODS FOR BARCODING ROOTPATH GENOMICS, INC. 2020-12-10 US disclosed
US-10759952-B2 Aqueous radiation curable inkjet inks AGFA NV (BE) 2020-09-01 US disclosed
CN-111601795-A Water-soluble 3-coumarin ketones 意大利艾坚蒙树脂有限公司 2020-08-28 CN disclosed
WO-2020036875-A1 HIGH THROUGHPUT CLONING OF PAIRED BIPARTITE IMMUNORECEPTOR POLYNUCLEOTIDES AND APPLICATIONS THEREOF ROOTPATH GENOMICS, INC. (US) 2020-02-20 WO disclosed
WO-2019204061-A1 MACROMERS AND COMPOSITIONS FOR PHOTOCURING PROCESSES POLY-MED, INC. (US) 2019-10-24 WO disclosed
US-20170114235-A1 AQUEOUS RADIATION CURABLE INKJET INKS AGFA NV (BE) 2017-04-27 US disclosed
EP-2960306-A1 Aqueous radiation curable inkjet inks AGFA GRAPHICS NV (BE) 2015-12-30 EP disclosed
WO-2015197472-A1 AQUEOUS RADIATION CURABLE INKJET INKS AGFA GRAPHICS NV (BE) 2015-12-30 WO disclosed
US-6488872-B1 Microfabricated devices and method of manufacturing the same THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2002-12-03 US disclosed