Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117062 | 0.91 | CFTR (0.41) | ESR1HTTNPC1RAB9ASMN1; SMN2 | |
| Lithium SCHEMBL29525491 | 0.90 | CFTR (0.40) | ESR1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12813050 | 0.90 | CFTR (0.40) | ESR1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28569551 | 0.90 | CFTR (0.40) | ESR1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7647274 | 0.90 | CFTR (0.40) | HTTNPC1RAB9ASMN1; SMN2TSHR | |
| Methoxymethane SCHEMBL29366991 | 0.87 | POLB (0.38) | MAPTPOLBHTTSMN1; SMN2LMNA | |
| SCHEMBL10632477 | 0.86 | LMNA (0.48) | SMN1; SMN2TSHRGAALMNARAPGEF4 | |
| Hypophosphorous Acid SCHEMBL30987241 | 0.85 | CFTR (0.37) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28390844 | 0.84 | CFTR (0.36) | MAPTPOLBKDM4EHTTSMN1; SMN2 | |
| SCHEMBL16705220 | 0.81 | LMNA (0.38) | HTTNPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |